Synonyms for defile

Most common

1. Sully — to make (someone or something) physically dirty or unclean; to befoul, to soil

2. Corrupt — to act inappropriately towards or vandalize (something sacred or special); to desecrate, to profane

3. Ravish — to deprive (someone) of their sexual chastity or purity, often not consensually; to deflower, to rape

Other

defilade

v. 1
To make (someone or something) physically dirty or unclean; to befoul, to soil.
v. 2
To act inappropriately towards or vandalize (something sacred or special); to desecrate, to profane.
To urinate on someone’s grave is an example of a way to defile it.
v. 3
To deprive (someone) of their sexual chastity or purity, often not consensually; to deflower, to rape.
The serial rapist kidnapped and defiled a six-year-old girl.
n. 1
A narrow passage or way (originally (military), one which soldiers could only march through in a single file or line), especially a narrow gorge or pass between mountains.

Plural: defiles → gorges, passes, ravines, passages…
Past participle: defiled
e.g. defiled → sullied, tarnished, polluted, fouled…

Use in printed books, per decade from 1850 to 2019.

3 letters: cut¹
4 letters: pass¹, rape¹, soil¹, foul¹, slur¹, blot¹, smut¹
5 letters: force¹, abuse², dirty², cloud¹, spoil¹, stain¹, smear¹, gorge¹, sully², taint¹
6 letters: poison², misuse², infect², injure², ravine², smudge¹, ravage², ravish, debase², befoul
7 letters: passage², corrupt², violate³, outrage², pervert², profane², tarnish², pollute², blacken², vitiate³, debauch
8 letters: dishonor³, besmirch, defilade
9 letters: dishonour, desecrate³
11 letters: contaminate⁴, constuprate

The small number after each word is its number of syllables (abuse² = 2 syllables).